While I am not in the rental business, I have this empty unit above part of my house. Friends have stayed in it. We have talked about renting it out by the night which would be a project for my wife — but she is working in Nicaragua right now.
Enter a solution: a local friend is looking for a way to make some money to go to college. She is going to manage it for me. It is very convenient to central Panajachel (less than 100 meters off Calle Santander) but also very private. The details and more photos are available here.
If you are interested, email me at email@example.com.